Postdoctoral Scientist (Microbiome Analysis)
Post Details
Job Title
Postdoctoral Scientist (Microbiome Analysis)
Post Number
1003537
Closing Date
31 Jan 2019
Grade
SC6
Starting Salary
£31,250 - £38,100
Hours per week
37
Project Title
Mucin-derived sialic acid metabolism in gut bacteria
Expected/Ideal Start Date
04 Feb 2019
Months Duration
12

Job Description

Main Purpose of the Job

Contribute to the experimental work of a BBSRC-funded grant investigating the metabolism of sialic acid in gut bacteria. The applicant will complete specific scientific tasks, contribute to the writing of publications and proposals, present results at project meetings and conferences, liaise with collaborators and contribute to day-to-day lab activities.

Key Relationships

The post-holder will work in the Gut Microbes & Health Programme and will be line-managed by Dr Nathalie Juge. They will work closely with PhD students and with Research Scientists in the Juge Group, as well as interacting with academic collaborators of the project.

Main Activities & Responsibilities

Percentage
Lead and carry-out experimental work
80
Contribute to the writing of publications and reports
10
Present results at project meetings, scientific conferences and outreach/translation events
5
Contribute to lab activities (meetings, Lab management, training etc)
5
As agreed with the line manager, any other duties commensurate with the nature of the post.

Person Profile

Education & Qualifications

Requirement
Importance
PhD (full award or expected within 6 months) in Biology (Biochemistry/Molecular Microbiology/Glycobiology)
Essential

Specialist Knowledge & Skills

Requirement
Importance
Molecular microbiology
Essential
Gut microbiome
Essential
Glycobiology
Desirable

Relevant Experience

Requirement
Importance
Anaerobic microbial growth assays
Essential
Microbiome profiling sequencing & analysis
Essential
Bioinformatics
Essential
Statistical analyses
Essential
Mouse work
Desirable
In vitro colon model
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent communication skills, both written and oral
Essential
High degree of commitment and motivation
Essential
Excellent interpersonal skills, with the ability to work well as part of a team
Essential
Excellent time management and organisational skills with the ability to meet objectives and deadlines
Essential
Ability to collaborate with internal and external stakeholders
Essential
Promotes and strives for continuous improvement
Essential

Additional Requirements

Requirement
Importance
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Ability to maintain confidentiality and security of information where appropriate
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Attention to detail
Essential
Willingness to work outside standard working hours when required
Essential
Promotes equality and values diversity
Essential
Animal personal license
Desirable

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

Department

Gut Microbes and Health

Group Details

The Juge Group focuses on investigating the molecular mechanisms mediating the interaction between gut bacteria and the mucus layer covering the gastrointestinal tract with a focus on mucin glycosylation. We use multidisciplinary approaches to investigate how gut bacteria utilise mucin glycans as nutrients or binding sites, and adapt to changes in the mucosal environment in health and disease. The Group comprises five PhD students and five post-doctoral scientists and regularly host undergraduate students and visiting scientists. The Group has extensive collaborations on the Norwich Research Park and internationally.

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Postdoctoral Scientist

Applications are invited for a Postdoctoral Scientist to join the Laboratory of Prof Nathalie Juge in the Gut Microbes and Health Programme at the Quadram Institute Bioscience (QIB).

Background:

The Juge Group focuses on investigating the molecular mechanisms mediating the interaction between gut bacteria and the mucus layer covering the gastrointestinal tract with a focus on mucin glycosylation. We use multidisciplinary approaches to investigate how gut bacteria utilise mucin glycans as nutrients or binding sites and adapt to changes in the mucosal environment in health and disease.

The Group comprises five PhD students and five post-doctoral scientists and regularly hosts undergraduate students and visiting scientists. The Group has extensive collaborations on the Norwich Research Park and internationally.

The role:

The post-holder will contribute to the experimental work of a BBSRC-funded grant investigating the metabolism of sialic acid in gut bacteria. Specifically, they will carry out in vitro work (anaerobic cultures, in vitro colon model) and in vivo colonisation (mouse models) and contribute to microbiome analyses.

The post-holder will work closely with other post-doctoral scientists and collaborators on the Norwich Research Park involved in the project. In addition to the proposed experimental work, the post-holder will contribute to the research by interacting with Research Scientists and PhD students in the Juge Group, writing up reports and publications, and presenting at relevant meetings and conferences.

The post-holder will also be encouraged to join public engagement activities. In addition, they will benefit from regular BBSRC-sponsored training courses in career development and transferable skills.

The ideal candidate:

Candidates should possess a PhD in a relevant biological field (such as Biology, Biochemistry, Molecular Microbiology or Glycobiology). They should have in-depth knowledge of molecular microbiology and the gut microbiome.

Experience of anaerobic microbial growth assays is essential, as are bioinformatics skills and experience of microbiome profiling sequencing and analysis. Experience of mouse work is desirable.

All candidates should possess excellent communication skills, both written and verbal. They should also have excellent interpersonal skills and the ability to work well as part of a team.

Additional information:

Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This is a full time post for a contract of 12 months.

We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience (formerly the Institute of Food Research), the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).

The closing date for applications will be 31st January 2019.

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.