Research Scientist (Clinical Metagenomics)
Post Details
Job Title
Research Scientist (Clinical Metagenomics)
Post Number
1003652
Closing Date
30 Apr 2019
Grade
SC6
Starting Salary
£31,250 - £38,100
Hours per week
37
Project Title
Development of key technologies for real-time diagnosis, surveillance and intervention of resistant-bacterial infections based on nanopore sequencing.
Expected/Ideal Start Date
01 May 2019
Months Duration
36

Job Description

Main Purpose of the Job

To optimise, transfer and implement a clinical metagenomics test for the diagnosis of lower respiratory tract infection.

Key Relationships

The post holder will work closely with a Chinese diagnostics company (Simcere), Chinese hospitals and a UK SME (Oppilotech).

Main Activities & Responsibilities

This project will implement nanopore metagenomics technology developed in the O'Grady group (recently published in Nature Biotechnology) for the rapid diagnosis of lower respiratory tract infection in Chinese hospitals.
As agreed with line manager, any other duties commensurate with the nature of the role

Person Profile

Education & Qualifications

Requirement
Importance
PhD in biological sciences or equivalent
Essential

Specialist Knowledge & Skills

Requirement
Importance
Metagenomics
Essential
Bioinformatics
Essential
Diagnostics
Essential
Sample preparation
Essential
Project management
Essential
Diagnostic performance evaluation
Essential
Microbiological culture
Essential

Relevant Experience

Requirement
Importance
Molecular biology and sequencing experience
Essential
A publication track record appropriate for career stage
Essential
Experience of scientific collaboration and supervision
Essential
Experience using nanopore sequencing
Desirable
Experience with host cell/DNA depletion, pathogen cell/DNA enrichment
Desirable
Experience with respiratory samples
Desirable
Experience running research projects
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Ability to cooperate to reach a common goal
Essential
Strong communication skills, both written and verbal
Essential
The ability to make decisions and take responsibility
Essential
The ability to manage deadlines even under stressful situations
Essential
Good interpersonal skills, with the ability to work well as part of a team
Essential

Additional Requirements

Requirement
Importance
Promotes equality and values diversity
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Willingness to work outside standard working hours when required
Essential
Attention to detail
Essential

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Microbes in the Food Chain

Group Details

The O'Grady lab is part of the Microbial Metagenomics Research Laboratory (MMRL), which focusses on translating metagenomics technologies for investigating human pathogens in different sample types.

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Research Scientist (Clinical Metagenomics)

Applications are invited for a Research Scientist to join the Laboratory of Dr Justin O’Grady in the Microbes in the Food Chain Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.

The role:

The O’Grady group is looking to recruit a Research Scientist on a prestigious Innovate UK UK-China AMR grant titled "Development of key technologies for real-time diagnosis, surveillance and intervention of resistant-bacterial infections based on nanopore sequencing". This is a 3 year post where the successful candidate will implement nanopore metagenomics technology developed in the O'Grady group (soon to be published in Nature Biotechnology) for the rapid diagnosis of lower respiratory tract infection in Chinese hospitals. The post holder will work closely with a Chinese diagnostics company (Simcere), Chinese hospitals and a UK SME (Oppilotech). The job will involve metagenomics method optimisation, technology transfer, analytical and clinical validation and a diagnostics trial in Chinese hospitals.

The ideal candidate:

The Research Scientist should have a PhD in biological sciences or equivalent. Relevant skills in clinical metagenomics and data analysis are required and previous experience running research projects is an advantage. The ideal candidate will also have molecular biology and sequencing experience, a publication track record appropriate for their career stage, and experience of scientific collaboration and supervision.

Additional information:

Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This post is for a contract of 3 years.

Interviews will be held on 6th May 2019.

We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).

The closing date for applications will be 16 April 2019.

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.