- Job Title
- Research Scientist (Clinical Metagenomics)
- Post Number
- Closing Date
- 24 Jul 2019
- Starting Salary
- £31,250 - £38,100
- Hours per week
- Project Title
- Development of key technologies for real-time diagnosis, surveillance and intervention of resistant-bacterial infections based on nanopore sequencing.
- Expected/Ideal Start Date
- 02 Sep 2019
- Months Duration
- Interview Date
- 02 Aug 2019
Main Purpose of the Job
To optimise, transfer and implement a clinical metagenomics test for the diagnosis of lower respiratory tract infection.
The post holder will work closely with a UK SME (Oppilotech), a Chinese diagnostics company (Simcere) and Chinese hospitals in Beijing.
Main Activities & Responsibilities
- This project will involve further development and implementation of a nanopore clinical metagenomics pipeline developed in the O'Grady group (recently published in Nature Biotechnology) for the rapid diagnosis of lower respiratory tract infection.
- As agreed with line manager, any other duties commensurate with the nature of the role
Education & Qualifications
- PhD in biological sciences or equivalent
Specialist Knowledge & Skills
- Genomics or metagenomics
- Molecular biology
- Infectious diseases diagnostics
- Sample preparation
- Microbiological culture
- Experience of scientific collaboration and supervision
- A publication track record appropriate for career stage
- Experience using nanopore sequencing
- Experience running research projects
- Experience with respiratory samples
Interpersonal & Communication Skills
- Ability to cooperate to reach a common goal
- Strong communication skills, both written and verbal
- The ability to make decisions and take responsibility
- The ability to manage deadlines even under stressful situations
- Good interpersonal skills, with the ability to work well as part of a team
- Promotes equality and values diversity
- Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
- Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
- Willingness to work outside standard working hours when required
- Attention to detail
Who We Are
Quadram Institute Bioscience
The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.
We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.
Microbes in the Food Chain
The O'Grady lab is part of the Microbial Metagenomics Research Laboratory (MMRL), which focusses on translating metagenomics technologies for investigating human pathogens in different sample types.
Research Scientist (Nanopore sequencing based Clinical Metagenomics)
Applications are invited for a Research Scientist to join the Laboratory of Dr Justin O’Grady in the Microbes in the Food Chain Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.
The O’Grady group is looking to recruit a Research Scientist on a prestigious Innovate UK UK-China AMR grant titled "Development of key technologies for real-time diagnosis, surveillance and intervention of resistant-bacterial infections based on nanopore sequencing". This is a 3 year post where the successful candidate will further develop and implement clinical metagenomics technology developed in the O'Grady group (published in Nature Biotechnology, June 2019) for the rapid diagnosis of lower respiratory tract infection . The post holder will work closely with a UK SME (Oppilotech), a Chinese diagnostics company (Simcere) and Chinese hospitals in Beijing. The job will involve metagenomics method optimisation, technology transfer, analytical and clinical validation and a co-ordination of a diagnostics trial. There will be the opportunity for travel to China (Beijing/Nanjing/Shanghai) 2-3 times per year for up to two weeks (candidates who speak Mandarin are very welcome to apply). There will also be the opportunity for the Research Scientist to develop their own relevant research interests and we actively encourage staff to apply for fellowships and grants to further their career.
The ideal candidate:
The Research Scientist should have a PhD in biological sciences or equivalent. They will have a background in genomics, metagenomics and/or molecular biology and will have an interest in clinical infectious diseases. Relevant skills in data analysis, diagnostics and running research projects are an advantage. The ideal candidate will also have a publication track record appropriate for their career stage, and experience of scientific collaboration and supervision.
Salary on appointment will be within the range £31,250 to £38,100 per annum depending on qualifications and experience. This post is for a contract of 3 years.
Interviews will be held on 2 Aug 2019.
We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.
As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
About the Quadram Institute:
The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).
The closing date for applications will be 24 July 2019.
The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.