Bioinformatician
Post Details
Job Title
Bioinformatician
Post Number
1003723
Closing Date
31 Jul 2019
Grade
SC6
Starting Salary
£31,625 - £38,575
Hours per week
37
Expected/Ideal Start Date
02 Sep 2019
Months Duration
36

Job Description

Main Purpose of the Job

We are seeking to appoint a Bioinformatician to support the research of the Gut Microbes and Health (GMH) Programme. The appointee will work specifically on supporting GMH projects (https://quadram.ac.uk/research_areas/gut-microbes-health/). The post holder will work closely with Group Leaders, research scientists and PhD students from the GMH Programme and with QIB bioinformaticians. The post-holder should have demonstrated experience of bioinformatics and familiarity with sequencing data (16S, metagenome, RNAseq, and transcriptomics). Experience in phylogeny, numerical ecology, visualisation of data or multivariate statistics are desirable, and the candidate should be fluent in at least one programming language (R/Perl/Python).

Key Relationships

The post holder will work closely with Group Leaders, research scientists and PhD students from the GMH ISP and with QIB bioinformaticians.

Main Activities & Responsibilities

Supporting and communicating with other bioinformaticians
Building bioinformatics pipelines
Productionising novel software methods
Supporting and performing bioinformatics analysis
Monitoring and managing computing and storage resources
Data submissions to public archives
Providing training and support to colleagues in bioinformatics
As agreed with line manager, any other duties commensurate with the nature of the post

Person Profile

Education & Qualifications

Requirement
Importance
Postgraduate degree, or equivalent, in bioinformatics, computing, computational biology, or a related computational subject
Essential
Research experience and/or a PhD
Desirable

Specialist Knowledge & Skills

Requirement
Importance
Proficiency in Linux
Essential
Ability to program in at least 1 programming language such as Python/Perl/R
Essential
Knowledge of bioinformatics analysis techniques and methods
Essential
Knowledge of next generation sequencing data formats
Desirable
Advanced knowledge of at least 1 modern programming language
Desirable

Relevant Experience

Requirement
Importance
Demonstrated experience of bioinformatics and familiarity with genome sequencing data (16S, metagenome, RNAseq, and transcriptomics)
Essential
Experience of researching/using/supporting external software packages
Desirable
Experience of working with Big Data
Desirable
Demonstrated experience in software development, documentation and code management
Desirable
Experience in phylogeny, numerical ecology, visualisation of data or multivariate statistics.
Desirable
Experience of working with biological analysis pipelines such as Galaxy, snake make, NextFlow
Desirable
Experience using cloud computing or high performance computing clusters
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Clear written and verbal communication skills
Essential
Ability to rapidly attain new technical skills and understanding of new technical concepts
Essential
A high level of interpersonal skills to be able to elicit complex requirements from, and convey complex information to, group members with different levels of technical knowledge
Essential
Ability to quickly adapt to new problems and ideas
Essential
Demonstrated ability to work independently, using initiative and applying problem solving skills
Essential

Additional Requirements

Requirement
Importance
Promotes equality and values diversity
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Willingness to work outside standard working hours when required
Essential
Attention to detail
Essential

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Gut Microbes and Health

Group Details

This post will sit within the core bioinformatics team for the Quadram Institute, and will provide dedicated support for one area in the Gut Microbes and Health Programme at QIB. The appointee will work specifically on supporting GMH projects (https://quadram.ac.uk/research_areas/gut-microbes-health/).

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Applications are invited for an enthusiastic and motivated Bioinformatician to join the Gut Microbes and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.

Gut Microbes and Health Programme

The microbes that live inside our guts are mostly a mystery to science. We know they have an impact on our health and wellbeing that extends far beyond the gut but science currently doesn't fully understand how or why. You can be part of this grand scientific endeavour to understand the microbes that live inside us all.

The Gut Microbes and Health Programme (https://quadram.ac.uk/research_areas/gut-microbes-health/) aims to obtain mechanistic knowledge on the role of the gut microbiome during normal healthy ageing in order to develop strategies that will improve lifelong health and wellbeing.

Our Programme is organised into three complementary themes, and is underpinned by two studies of very young (pregnancy and early life) and ageing/elderly East Anglia-based populations that form the basis for coordinated investigations addressing the mechanistic basis of microbiome-host interactions in health. Next generation sequencing, and bioinformatic/computational approaches, complemented by ongoing lab-based studies, will be used to probe the complexity of the relationship between the gut microbiome and host.

The role

As a bioinformatician supporting this Programme, you will work with vast datasets of metagenomic sequence data (truly BigData) and will gain experience with cutting edge sequencing technologies, such as those from Nanopore and PacBio. At your disposal will be a massive OpenStack cloud computing system with hundreds of terabytes of disk space and thousands of computing cores.

You will be embedded within the core bioinformatics team for the Quadram Institute, so will be surrounded by experienced bioinformaticians, providing a friendly environment to enhance your skills. In this rapidly changing field you will have the opportunity to work with researchers on publishing new methodologies, which we make available as open source software on GitHub (https://github.com/quadram-institute-bioscience/).

The ideal candidate

Ideal candidates will have a postgraduate degree in computing, computational biology, bioinformatics or a related computational subject, a strong proficiency in Linux, and an ability to program in at least one programming language to an advanced level. They will also have excellent communication and interpersonal skills, as the post will involve working with staff across the Institute.

Additional information

Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This is a fulltime contract for a period of 3 years.

We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).