Research Scientist (Gut Systems Biology)
Post Details
Job Title
Research Scientist (Gut Systems Biology)
Post Number
1003727
Closing Date
8 Aug 2019
Grade
SC6
Starting Salary
£31,625 - £38,575
Hours per week
37
Project Title
Gut Systems Biology
Expected/Ideal Start Date
01 Sep 2019
Months Duration
30

Job Description

Main Purpose of the Job

Applications are invited for a Research Scientist to join the group of Dr Tamas Korcsmaros in the Gut Microbes and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK. They will work on network and systems biology related projects focusing on gut homeostasis, intestinal host-microbe interactions, autophagy and signalling networks as well as data integration from various omic sources to develop new models and in silico predictions.

Key Relationships

The post holder will work with the research leaders and postdocs in the Gut Microbes and Health ISP as well as other researchers in the Quadram Institute. Also, the post holder will have direct connection to the researchers in the Earlham Institute, and will contribute to national and international collaborations, involving Kings College London, University of Cambridge, KU Leuven, Universoty of Toronto.

Main Activities & Responsibilities

Percentage
Computational data analysis
25
Developing new computational models
20
Leading and contributing to preparations of publications
20
Supervising students
15
Contributing to grant applications
10
Public engagement and training (internal and external)
10
As agreed with line manager, any other duties commensurate with the nature of the role

Person Profile

Education & Qualifications

Requirement
Importance
PhD degree related to Computer Science, Microbiology, Gut Biology or Computational Biology
Essential

Specialist Knowledge & Skills

Requirement
Importance
Evidence expertise in systems biology and network modelling
Essential
Working in a Linux environment (local and remote)
Essential
HPC (slurm) and Python
Essential
Working with R or Julia or similar data science oriented script languages
Desirable

Relevant Experience

Requirement
Importance
Experience in git and version/source control systems
Essential
Experience with transcriptome and/or proteomic data analysis.
Desirable
Experience in relational or document base database systems (MySQL, PostgreSQL, MongoDB)
Desirable
Knowledge in containerization (Docker)
Desirable
Experience in Javascript (client or server side)
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Good communication skills, both written and verbal
Essential
Evidence to work in a multidisciplinary environment/project
Essential
Good presentational skills
Essential
Good interpersonal skills, with the ability to work well as part of a team
Essential

Additional Requirements

Requirement
Importance
Attention to detail
Essential
Promotes equality and values diversity
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Willingness to work outside standard working hours when required
Essential

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Gut Microbes and Health

Group Details

The Korcsmaros group is a a multi-disciplinary group, established 5 years ago that combines computational and experimental approaches to predict, analyse and validate host-microbe interactions in the gut. The main interest of the group is related to the regulation of autophagy by microbes and upon disease conditions such as inflammatory bowel disease (IBD). The group is specialised in developing novel methods that combines systems biology, signalling networks with microbiome and clinical data, with a special interest to create organoid based analytical platforms. The group is based in both the QIB specialising in state-of-the-art microbiome and health research, and the Earlham Institute (EI), also on the Norwich Research Park, specialising in genomics and systems biology. The joint affiliation provides access to the brand-new QI facility, which houses a large endoscopy unit and state-of-the-art microbiome and clinical research areas, allowing direct access to patient samples and microbiome laboratories as well as to EI’s cutting-edge sequencing platforms and one of Europe’s largest computing infrastructures for life sciences.

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Research Scientist (Gut Systems Biology)

Applications are invited for a Research Scientist to join the Gut Systems Biology group of Dr Tamas Korcsmaros in the Gut Microbes and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.

Background:

The Korcsmaros group (https://quadram.ac.uk/tamas-korcsmaros/) is a multi-disciplinary group that combines computational and experimental approaches to predict, analyse and validate host-microbe interactions in the gut. The main interest of the group is related to the regulation of autophagy by microbes and upon disease conditions such as inflammatory bowel disease (IBD). The group is specialised in developing novel methods that combine systems biology, signalling networks with microbiome and clinical data, with a special interest in creating organoid based analytical platforms. For further details on the current research projects of the group, see https://www.earlham.ac.uk/korcsmaros-group#Projects.

The group is based in both QIB, specialising in state-of-the-art microbiome and health research, and the Earlham Institute (EI), specialising in genomics and systems biology. Both institutes are based on the Norwich Research Park. The joint affiliation provides access to the brand-new Quadram Institute building, which houses a large endoscopy unit and state-of-the-art microbiome and clinical research areas, allowing direct access to patient samples and microbiome laboratories as well as to EI’s cutting-edge sequencing platforms and one of Europe’s largest computing infrastructures for life sciences. For further information about why Norwich is great place to work and live in, please check these links: https://quadram.ac.uk/about/join-us/; http://www.earlham.ac.uk/living-norfolk

The role:

The Research Scientist will work on network and systems biology related projects focusing on gut homeostasis, intestinal host-microbiome interactions, autophagy and signalling networks as well as data integration from various omic sources to develop new models and in silico predictions.

The Research Scientist will be an enthusiastic and motivated individual who will participate in studying integrative and systems-level problems. The position will be computational, offering flexibility and opportunities for personal development. The post holder will contribute to supervising students and to grant and manuscript writing.

This 30-months funded position will give the applicant the opportunity to have an active role in building new projects within the Gut Microbes and Health Programme exploiting in-house generated data, offering independence, responsibility and scientific freedom.

The post holder will have plenty of opportunities to learn novel techniques, data management technologies, interact with researchers with different backgrounds and work with cutting-edge approaches. Also, the post holder could participate in training and receive direct advice to develop to be a successful and happy independent researcher.

The ideal candidate:

Applicants should have a PhD related to Computer Science, Microbiology, Gut Biology or Computational Biology. They should be able to evidence expertise in systems biology and network modelling and have knowledge of working with R or Julia or similar data science-oriented script languages. The successful candidate will have experience in git and version/source control systems, knowledge of working in a Linux environment (local and remote) and skills in HPC (slurm) and Python.

Additional information:

Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This is a fulltime post for a contract of 30 months.

For further information and details of how to apply, please visit our web site https://jobs.quadram.ac.uk or contact the Human Resources team on 01603 450462 or nbi.recruitment@nbi.ac.uk quoting reference 1003727.

We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

The closing date for applications will be 8 August 2019.

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.