Research Scientist (Molecular Microbiology)
Post Details
Job Title
Research Scientist (Molecular Microbiology)
Post Number
1003737
Closing Date
20 Aug 2019
Grade
SC6
Starting Salary
£31,625 - £38,575
Hours per week
37
Project Title
GMH-ISP RA. Molecular Microbiologist
Expected/Ideal Start Date
02 Sep 2019
Months Duration
40
Interview Date
28 Aug 2019

Job Description

Main Purpose of the Job

Join a project striving to understand how species within the microbiome interact with the gut to affect health. The appointee will work across the research groups of Profs Carding and Warren to develop and lead on studies investigating pathways and mediators of microbe-microbe and microbe-host interactions in the gut. There will be a particular focus on bacterial intracellular compartments and extracellular microvesicles and how they influence intestinal mucosal cell physiology and host metabolism.

Key Relationships

Internal: Line manager, group members and, as necessary, other researchers, research support staff and students across the Institute.
External: Collaborators

Main Activities & Responsibilities

Percentage
Identify, plan, carry out and modify experiments to meet the objectives of the project
65
Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media
10
Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence
10
Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements
5
Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities
5
As agreed with line manager, any other duties commensurate with the nature of the role
5

Person Profile

Education & Qualifications

Requirement
Importance
PhD or equivalent in biological sciences, microbiology or a related discipline
Essential

Specialist Knowledge & Skills

Requirement
Importance
Knowledge of bacterial physiology and genetics
Essential
Practical experience of the genetic manipulation of Gram negative bacteria
Essential
Knowledge of the human (gut) microbiome and its means and methods of analysis
Essential
Knowledge and/or experience of metagenomics -sequence data generation and analysis
Desirable
Knowledge of mucosal/gut immunology
Desirable

Relevant Experience

Requirement
Importance
Molecular and cellular bacteriology
Essential
High quality publications in peer reviewed journals
Essential
Mentoring, training and/or supervision of undergraduate/postgraduate students
Desirable
Excellent literature review and interpretation skills
Desirable
Animal cell culture
Desirable
Experimental in vivo models to investigate host-microbe interactions
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent written and verbal communication skills
Essential
Willingness to work both independently and as part of a team
Essential
Creative approach to problem solving
Essential
Enthusiasm for and ability to mentor and supervise junior colleagues
Desirable

Additional Requirements

Requirement
Importance
Attention to detail
Essential
Promotes equality and values diversity
Essential
Willingness to work outside standard working hours as and when required
Essential
Willingness to undertake training relevant to the role
Essential
Willingness to attend collaborator meetings and conferences within and outside the UK
Essential

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

The Quadram Institute is a diverse and multicultural scientific community. We thrive on our international and European links, appointing staff from across the world. We expect this to continue post Brexit. However, any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or nbi.recruitment@nbi.ac.uk.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Microbes in the Food Chain

Group Details

The appointee will work across the research groups of Profs Carding and Warren within the Gut Microbes and Health research programme at the Quadram Institute. This research programme is transdisciplinary and is focused on studying the role of the gut microbiome in normal healthy ageing and developing strategies to improve lifelong health and wellbeing using a systems-level experimental approach. The research uses innovative in vivo, in vitro, and in silico tools/models in tandem with two population-based longitudinal studies in early life (pregnant mothers and their infants: the PEARL study) and later life (elderly individuals at risk of developing dementia: the MOTION study), to define and refine novel intervention strategies that will promote gut and gut-organ linked (brain and liver) health.

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Applications are invited for an exceptional Research Scientist to join an exciting project within the research groups of Profs Carding and Warren at the Quadram Institute Bioscience.

Quadram Institute:

We offer a vibrant, innovative and supportive workplace environment, competitive salaries, generous holiday entitlement and an excellent defined contribution pension scheme.

Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building.

The role:

Join a project investigating the human intestinal microbiome and the role that bacterial microvesicles play in microbe-microbe and microbe-host interactions in establishing and maintaining gut health throughout the life course.

The successful candidate will be responsible for the design and execution of experiments utilising methods and protocols for microvesicle isolation and characterisation. They will also investigate the molecular mechanisms regulating their production by key members of the intestinal microbiota.

This role is based at the Quadram Institute Bioscience, the post-holder may key be required to visit the University of Kent to acquire relevant skills and develop protocols for intracellular microvesicle characterisation.

The ideal candidate:

Candidates should possess a PhD in biological sciences or microbiology, or related subject. It is essential that candidates have experience or knowledge of the latest techniques and experimental systems for studying human commensal bacteria. A good record of first author publications in high quality peer reviewed journals is also important.

Additional information:

Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This post is a fulltime role for a period of 40 months.

We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute.