- Job Title
- Research Scientist (Molecular Microbiology)
- Post Number
- Closing Date
- 20 Aug 2019
- Starting Salary
- £31,625 - £38,575
- Hours per week
- Project Title
- GMH-ISP RA. Molecular Microbiologist
- Expected/Ideal Start Date
- 02 Sep 2019
- Months Duration
- Interview Date
- 28 Aug 2019
Main Purpose of the Job
Join a project striving to understand how species within the microbiome interact with the gut to affect health. The appointee will work across the research groups of Profs Carding and Warren to develop and lead on studies investigating pathways and mediators of microbe-microbe and microbe-host interactions in the gut. There will be a particular focus on bacterial intracellular compartments and extracellular microvesicles and how they influence intestinal mucosal cell physiology and host metabolism.
Internal: Line manager, group members and, as necessary, other researchers, research support staff and students across the Institute.
Main Activities & Responsibilities
- Identify, plan, carry out and modify experiments to meet the objectives of the project
- Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media
- Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence
- Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements
- Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities
- As agreed with line manager, any other duties commensurate with the nature of the role
Education & Qualifications
- PhD or equivalent in biological sciences, microbiology or a related discipline
Specialist Knowledge & Skills
- Knowledge of bacterial physiology and genetics
- Practical experience of the genetic manipulation of Gram negative bacteria
- Knowledge of the human (gut) microbiome and its means and methods of analysis
- Knowledge and/or experience of metagenomics -sequence data generation and analysis
- Knowledge of mucosal/gut immunology
- Molecular and cellular bacteriology
- High quality publications in peer reviewed journals
- Mentoring, training and/or supervision of undergraduate/postgraduate students
- Excellent literature review and interpretation skills
- Animal cell culture
- Experimental in vivo models to investigate host-microbe interactions
Interpersonal & Communication Skills
- Excellent written and verbal communication skills
- Willingness to work both independently and as part of a team
- Creative approach to problem solving
- Enthusiasm for and ability to mentor and supervise junior colleagues
- Attention to detail
- Promotes equality and values diversity
- Willingness to work outside standard working hours as and when required
- Willingness to undertake training relevant to the role
- Willingness to attend collaborator meetings and conferences within and outside the UK
Who We Are
Quadram Institute Bioscience
The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.
We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.
The Quadram Institute is a diverse and multicultural scientific community. We thrive on our international and European links, appointing staff from across the world. We expect this to continue post Brexit. However, any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or firstname.lastname@example.org.
Microbes in the Food Chain
The appointee will work across the research groups of Profs Carding and Warren within the Gut Microbes and Health research programme at the Quadram Institute. This research programme is transdisciplinary and is focused on studying the role of the gut microbiome in normal healthy ageing and developing strategies to improve lifelong health and wellbeing using a systems-level experimental approach. The research uses innovative in vivo, in vitro, and in silico tools/models in tandem with two population-based longitudinal studies in early life (pregnant mothers and their infants: the PEARL study) and later life (elderly individuals at risk of developing dementia: the MOTION study), to define and refine novel intervention strategies that will promote gut and gut-organ linked (brain and liver) health.
Applications are invited for an exceptional Research Scientist to join an exciting project within the research groups of Profs Carding and Warren at the Quadram Institute Bioscience.
We oﬀer a vibrant, innovative and supportive workplace environment, competitive salaries, generous holiday entitlement and an excellent defined contribution pension scheme.
Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building.
Join a project investigating the human intestinal microbiome and the role that bacterial microvesicles play in microbe-microbe and microbe-host interactions in establishing and maintaining gut health throughout the life course.
The successful candidate will be responsible for the design and execution of experiments utilising methods and protocols for microvesicle isolation and characterisation. They will also investigate the molecular mechanisms regulating their production by key members of the intestinal microbiota.
This role is based at the Quadram Institute Bioscience, the post-holder may key be required to visit the University of Kent to acquire relevant skills and develop protocols for intracellular microvesicle characterisation.
The ideal candidate:
Candidates should possess a PhD in biological sciences or microbiology, or related subject. It is essential that candidates have experience or knowledge of the latest techniques and experimental systems for studying human commensal bacteria. A good record of first author publications in high quality peer reviewed journals is also important.
Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience. This post is a fulltime role for a period of 40 months.
We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.
As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
About the Quadram Institute:
The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute.