- Job Title
- Research Assistant (Gut Carbohydrate Fermentation)
- Post Number
- Closing Date
- 5 Sep 2019
- Starting Salary
- £24,815 - £30,270
- Hours per week
- Project Title
- Starch structure and behaviour in the colon
- Expected/Ideal Start Date
- 14 Oct 2019
- Months Duration
- Interview Date
- 18 Sep 2019
Main Purpose of the Job
A Research Assistant is sought to assist with ongoing experiments in the Warren lab using the colon model system. In particular, these will be continuing the labs main focus through our BBSRC ISP grant on carrying out colon model experiments using a wide range of starches from different sources as substrates within the model colon system based at QIB. This will require the post holder to set up and run the model colon system. This will be followed by metabolite analysis using 1H NMR, which the post holder will be expected to assist with, both preparing samples and subsequent analysis. The post holder will also be expected to carry out DNA extraction for subsequent 16S sequencing. Additionally, the post holder will assist with starch structural analysis methods including size exclusion chromatography and differential scanning calorimetry for analysis of substrates.
The post holder will report directly to Dr. Fred Warren as line manager, and to Prof. Pete Wilde, acting head of Food, Innovation and Health. The post holder will also work closely with Hannah Harris, the ISP PDRA in the Warren group.
Main Activities & Responsibilities
- Assisting with in vitro model colon experiments
- Preparing samples for 1H NMR analysis and DNA extraction for illumina sequencing
- Starch structural analysis (debranching samples for SEC analysis, DSC experiments)
- Data analysis and assisting in preperation of manuscripts
- Assisting students/visitors with experiments
- As agreed with line manager, any other duties commensurate with the nature of the role
Education & Qualifications
- BSc in biology, biochemistry, microbiology or related subject
- MSc or PhD in biology, biochemistry, microbiology or related subject
Specialist Knowledge & Skills
- Skilled in using colon models
- DNA extraction
- Some knowledge of metabolomic methods
- Carbohydrate structural analysis
- Experience with batch fermentation/colonic systems
- Experience with microbiological techniques/anaerobic culture methods
- Experience handling human samples
Interpersonal & Communication Skills
- Excellent time management and organisational skills
- Ability to follow instructions/Standard Operating Procedures
- Excellent communication skills, both written and oral
- Good interpersonal skills, with the ability to work well as part of a team
- Attention to detail
- Promotes equality and values diversity
- Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
- Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
- Willingness to work outside standard working hours when required
Who We Are
Quadram Institute Bioscience
The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.
We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.
The Quadram Institute is a diverse and multicultural scientific community. We thrive on our international and European links, appointing staff from across the world. We expect this to continue post Brexit. However, any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or firstname.lastname@example.org.
Food Innovation and Health
The Warren group is a research group focussed on carbohydrate structure, function and behaviour in the GI tract. We currently comprise three PhD students (with a fourth starting in October) and two post-docs. We are a diverse group, from a range of scientific backgrounds including chemistry, microbiology and nutrition and bring our expertise together to explore the structuring and functionality of carbohydrates
Research Assistant (Gut Carbohydrate Fermentation)
Applications are invited for a Research Assistant to join the Laboratory of Dr Fred Warren in the Food Innovation and Health Programme at Quadram Institute Bioscience (QIB), based in Norwich, UK.
The Food Innovation and Health Programme is focussed on understanding how individual foods and diets can help us to maintain and improve our health, and developing innovative foods that promote healthy ageing.
The Research Assistant will assist with ongoing experiments in the Warren lab using the colon model system. In particular, these will be continuing the lab's main focus through our BBSRC ISP grant on carrying out colon model experiments using a wide range of starches from different sources as substrates within the model colon system based at QIB. This will require the post holder to set up and run the model colon system.
This will be followed by metabolite analysis using 1H NMR, which the post holder will be expected to assist with, both preparing samples and subsequent analysis. The post holder will also be expected to carry out DNA extraction for subsequent 16S sequencing.
Additionally, the post holder will assist with starch structural analysis methods including size exclusion chromatography and differential scanning calorimetry for analysis of substrates.
The ideal candidate:
We are looking to hire a Research Assistant with at a minimum a BSc in a biological sciences subject, preferably also with a higher degree, to assist with our ongoing research projects.
We are looking for an enthusiastic and dedicated team member with a passion for linking structure and composition of foods to the microbiome and health outcomes.
Applicants should have Excellent time management and organisational skills. Previous experience with batch fermentation/colonic systems, microbiological techniques/anaerobic culture methods and handling human samples is desirable.
Salary on appointment will be within the range £24,815 to £30,270 per annum depending on qualifications and experience. This is a full time post for a contract of 8 months.
Interviews will be held on 18 September 2019.
Please note, this post does not meet UKVI requirements to provide Tier 2 visa sponsorship.
We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.
As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
About the Quadram Institute:
The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).
The closing date for applications will be 5 September 2019.
The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.