Research Scientist (Antimicrobial Resistance) Maternity Cover
Post Details
Job Title
Research Scientist (Antimicrobial Resistance) Maternity Cover
Post Number
1003811
Closing Date
8 Dec 2019
Grade
SC6
Starting Salary
£31,625 - £38,575
Hours per week
37
Project Title
Investigating mechanisms of antimicrobial resistance and adaptation to stress in bacterial biofilms
Expected/Ideal Start Date
03 Feb 2020
Months Duration
12
Interview Date
06 Jan 2020

Job Description

Main Purpose of the Job

An exciting opportunity is available for an outstanding Research Scientist to join the Webber group at the Quadram Institute on the Norwich Research Park in the UK, to contribute to fundamental research into bacterial biofilms.

The ultimate aim of the work is to understand bacterial behaviour in relevant conditions to the food chain in order to develop improved interventions to reduce bacterial survival and prevent development of antimicrobial resistance in order to benefit both human and animal health.

The job holder will investigate the mechanisms of bacterial resistance to antimicrobials in biofilms and to help understand the bacterial responses to stresses encountered in the gut and food chain and the impact of these stresses on development of antimicrobial resistance.
Further more, the job holder will develop and apply biofilm models which can be used to investigate bacterial responses to stress at both population and single cell levels.

Key Relationships

Internal: With the line manager, Dr Mark Webber, group members, other researchers, research support staff and students across the Institute and wider Norwich Research Park (NRP).
External: Collaborators based on the NRP and external to Norwich

Main Activities & Responsibilities

Percentage
Use of biofilm models, development of mixed communities biofilms, recovery and analysis of resistant mutants using whole-genome sequencing, confocal microscopy to investigate bacterial viability, gene mobility and expression of genes of interest in situ, flow cytometry to investigate population level responses to stress. Creation of directed mutants in genes of interest.
45
Contribution to laboratory management, group meetings and interactions with collaborators
15
Preparation of manuscripts, reports and seminars
15
Training and supervision of other group members
10
Present research findings at project meetings, scientific conferences and outreach/translation events
5
Ordering materials as and when necessary
5
As agreed with the line manager, any other duties commensurate with the nature of the post
5

Person Profile

Education & Qualifications

Requirement
Importance
A PhD (full award or expected within 6 months) or equivalent in a relevant subject (e.g. Microbiology, Molecular Genetics, Biochemistry)
Essential

Specialist Knowledge & Skills

Requirement
Importance
Molecular genetics
Essential
Single cell analysis of bacterial populations
Desirable
Basic Bioinformatics skills
Desirable
Antimicrobial susceptibility testing
Desirable
Good publication record in peer-reviewed scientific journals
Desirable

Relevant Experience

Requirement
Importance
Hands on experience with molecular genetics
Essential
Experience of oral research presentations
Essential
Proven record in scientific writing
Essential
Experience with antimicrobial susceptibility testing
Desirable
Experience with single cell analysis of bacterial populations
Desirable
Hands-on experience with microbial biofilms
Desirable
Experience with confocal microscopy
Desirable
Experience with flow cytometry
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent communication skills, both written and oral, including the ability to present complex information with clarity
Essential
Ability to collaborate with internal and external stakeholders
Essential
Highly committed and motivated to succeed
Essential
Excellent time management and organisational skills
Essential
Ability to prioritise
Essential
Accurate record keeping
Essential
Ability to work under pressure and meet deadlines
Essential
Good interpersonal skills, able to work as part of a team
Essential
Demonstrated ability to work independently, using initiative and applying problem solving skills
Essential
Ability to follow instructions/standard operating procedures
Essential

Additional Requirements

Requirement
Importance
Ability to undertake occasional travel (national/international) related to collaborations and/or seminars
Essential
Willingness to undertake any necessary training for the role
Essential
Ability to maintain confidentiality and security of information where appropriate
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting the aims of the Institute
Essential
Willingness to work outside standard working hours when required
Essential
Promotes and strives for continuous improvement
Essential
Attention to detail
Essential
Promotes equality and values diversity
Essential
Ability to think creatively, contribute new ideas, troubleshoot
Desirable

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

The Quadram Institute is a diverse and multicultural scientific community. We thrive on our international and European links, appointing staff from across the world. We expect this to continue post Brexit. However, any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or nbi.recruitment@nbi.ac.uk.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Microbes in the Food Chain

Group Details

The Webber group studies bacterial responses to antimicrobial stress with a focus on how antibiotic resistance can evolve in biofilms. This project will use various biofilm models and investigate bacterial survival, gene exchange and gene expression at single cell and population levels. The project will exploit state of the art facilities for genomics, flow cytometry and microscopy to understand bacterial behaviour and mechanisms of resistance. Work will focus on enteric pathogens including but not necessarily limited to Salmonella and E. coli. QIB and the Webber group will provide you with a stimulating, multidisciplinary training environment that will assist you in your successful scientific development.

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Research Scientist (Antimicrobial Resistance) Maternity Cover

An exciting opportunity is available for an outstanding Research Scientist to join the Webber group at the Quadram Institute on the Norwich Research Park in the UK, to contribute to fundamental research into bacterial biofilms.

The role:

This project will use various biofilm models and investigate bacterial survival, gene exchange and gene expression at single cell and population levels. The project will exploit state of the art facilities for genomics, flow cytometry and microscopy to understand bacterial behaviour and mechanisms of resistance. Work will focus on enteric pathogens including but not necessarily limited to Salmonella and E. coli. QIB and the Webber group will provide you with a stimulating, multidisciplinary training environment that will assist you in your successful scientific development.

The ideal candidate:

Candidates are expected to have a PhD in a relevant subject area (e.g. Microbiology, Molecular Genetics, Biochemistry). They will have knowledge of and hands on experience with molecular genetics. Knowledge and skills with single cell analysis of bacterial populations and bioinformatics skills are both desirable.

Additional information:

Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience.

This is a maternity cover contract expected to last for 12 months, this may be shorter or longer depending when the absent employee returns to work.

Informal enquiries can be made to mark.webber@quadram.ac.uk.

Interviews will be held on 6 January 2020, with an anticipated start date in February 2020.

We are committed to equal opportunities and welcome applications from all sectors of society.  The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values.  To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute at the forefront of a new era in food and health research. Its mission is to understand how food and the gut microbiota are linked to the promotion of health and the prevention of disease. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a new state-of-the-art building. The Quadram Institute is based on the Norwich Research Park, one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).

The closing date for applications will be 8 December 2019. 

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.