Research Scientist (Genomic Epidemiology / Microbial Genomics)
Post Details
Job Title
Research Scientist (Genomic Epidemiology / Microbial Genomics)
Post Number
1003832
Closing Date
30 Jan 2020
Grade
SC6
Starting Salary
£31,625 - £38,575
Hours per week
37
Expected/Ideal Start Date
03 Feb 2020
Months Duration
30

Job Description

Main Purpose of the Job

Applications are invited for a Research Scientist to join the group of Dr Alison Mather at Quadram Institute Bioscience (QIB), based in Norwich, UK.

To analyse existing large datasets of microbial whole genome sequences with extensive metadata, using relevant bioinformatics tools and pipelines to inform our understanding of the biology, evolution, spread and source attribution of bacterial pathogens and antimicrobial resistance (AMR) across the One Health spectrum.

Key Relationships

Internal: With the line manager, Dr Alison Mather, group members and other researchers and research support staff across the Institute. External: Collaborators

Main Activities & Responsibilities

Bioinformatics/molecular epidemiology analysis of AMR and bacteria across the One Health spectrum
Preparation of manuscripts and seminars
Present research findings at project meetings, scientific conferences and outreach/translation events
Contribute to laboratory management, group meetings and interactions with collaborators
As agreed with the line manager, any other duties commensurate with the nature of the post

Person Profile

Education & Qualifications

Requirement
Importance
A PhD in a relevant subject (e.g. Computational Biology, Microbiology, Molecular Genetics, Bioinformatics, Epidemiology or related discipline)
Essential

Specialist Knowledge & Skills

Requirement
Importance
Understanding of high-throughput sequencing and microbial genomics
Essential
Experience with quantitative data analysis
Essential
Experience with the linux environment
Essential
Understanding of antimicrobial resistance in bacteria
Desirable
Good publication record in peer-reviewed scientific journals commensurate with experience
Desirable
Experience with HPC and containers
Desirable

Relevant Experience

Requirement
Importance
Proven record in scientific writing commensurate with experience
Essential
Expertise using analysis software e.gl. R, Stata
Essential
Experience of oral research presentations
Essential
Experience with large sequence datasets
Desirable
Hands-on experience with microbial genome sequencing and analysis
Desirable
Experience with a high level programming language e.g. C, python, perl
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent communication skills, both written and oral, including the ability to present complex information with clarity
Essential
Ability to collaborate with internal and external stakeholders
Essential
Good interpersonal skills, able to work as part of a team
Essential
Accurate record keeping
Essential
Ability to think creatively, contribute new ideas, troubleshoot
Desirable

Additional Requirements

Requirement
Importance
Promotes equality and values diversity
Essential
Willingness to undertake any necessary training for the role
Essential
Ability to undertake occasional travel (national/international) related to collaborations and/or seminars
Essential
Ability to maintain confidentiality and security of information where appropriate
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Attention to detail
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Willingness to work outside standard working hours when required
Essential

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

The Quadram Institute is a diverse and multicultural scientific community. We thrive on our international and European links, appointing staff from across the world. We expect this to continue post Brexit. However, any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or nbi.recruitment@nbi.ac.uk.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Microbes in the Food Chain

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Research Scientist (Genomic Epidemiology / Microbial Genomics)

Applications are invited for a Research Scientist to join the group of Dr Alison Mather at Quadram Institute Bioscience (QIB), based in Norwich, UK.

Background:

The post holder will join a fun, international and supportive group of bioinformaticians, microbiologists, epidemiologists and molecular ecologists. We work to understand the evolution, origins and transmission of bacteria between different host populations, with a focus on bacteria that are resistant to antimicrobial drugs. We work with many external collaborators, including the Food Standards Agency and public health laboratories (both animal and human) in the UK and abroad.

This position will entail working on microbial genomes obtained from across the One Health spectrum (humans, food, animals, the environment) to address key questions such as the relative contribution from different sources to the AMR and pathogen burden in humans. This will be achieved using a combination of approaches, including short-and long-read whole genome sequencing, bioinformatics analyses of large datasets and statistical/epidemiological analyses.

The role:

The successful post holder will analyse and interpret existing large collections of microbial whole-genome sequence data from Illumina and Oxford Nanopore MinION technologies using various bioinformatics approaches to address the project aims. The post holder will occasionally present research findings at project meetings, scientific conferences and outreach/training events. There is scope to develop new projects within the team and collaborate with other groups (including a dedicated team of bioinformaticians) as well - creativity is welcome! 

The ideal candidate:

Candidates should have a PhD in a relevant subject (e.g. Computational Biology, Microbiology, Molecular Genetics, Bioinformatics, Epidemiology or related discipline), and experience in analysing microbial sequencing data. They should also possess a proven record in scientific writing and interpretation of data, and excellent communication and interpersonal skills.

Additional information:

Salary on appointment will be within the range £31,625 to £38,575 per annum depending on qualifications and experience.

This is a full time contract for 2.5 years, or until 30th September 2022.

We are committed to equal opportunities and welcome applications from all sectors of society. The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values. To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).

The closing date for applications will be 30 January 2020. 

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.