Research Scientist (Bacterial Lifestyles)
Post Details
Job Title
Research Scientist (Bacterial Lifestyles)
Post Number
1004126
Closing Date
9 Nov 2021
Grade
SC6
Starting Salary
£32,578 - £39,938
Hours per week
37
Project Title
Research Scientist (Bacterial Lifestyles)
Expected/Ideal Start Date
03 Jan 2022
Months Duration
41
Interview Date
29 Nov 2021

Job Description

Main Purpose of the Job

An exciting opportunity is available for an outstanding Research Scientist to join the Whitchurch group at the Quadram Institute on the Norwich Research Park in the UK. The post holder will contribute to fundamental research into bacterial lifestyles. The ultimate aim of the work is to understand alternate bacterial lifestyles in order to develop improved interventions to benefit both human and animal health.

The job holder will develop and utilise molecular microbiology, genetic, cell biology and microscopy techniques to investigate alternate bacterial lifestyles (eg biofilms, cell wall deficiency) to understand their roles in the bacterial survival, human health, and antimicrobial resistance.

The position will involve working with limited supervision to carry out individual and collaborative research projects relevant to the overall needs of the research programme. The work will also involve supervision of staff and students and general group management.

The project will exploit state of the art facilities for microscopy and genomics. Quadram Institute Bioscience and the Whitchurch group will provide you with a stimulating, multidisciplinary training environment that will assist you in your successful scientific development.

Key Relationships

Internal: Line manager (Cynthia Whitchurch), group members and, as necessary, other researchers, research support staff and students across the Institute.

External: Academic collaborators and industry partners

Main Activities & Responsibilities

Percentage
Identify, plan, carry out and modify experiments to meet the objectives of the project
45
Prepare results, reports and manuscripts for publication in leading scientific journals and other relevant media
15
Collaborate with colleagues within the Institute in the development of original and world-class research, including contributing to research proposals and grant applications
10
Liaise with industry and other external stakeholders
5
Ensure research and record keeping is carried out in accordance with good practice, Scientific Integrity and in compliance with local policies and any legal requirements
5
Continually strive for excellence, seeking out and acting on feedback and relevant learning and development opportunities
5
Contribute to the smooth running of the group, including the effective use of resources, supervision of visitors to the laboratory and assisting with training others, encouraging scientific excellence
5
As agreed with line manager, any other duties commensurate with the nature of the post
5
Disseminate research findings through presentations to various audiences at internal, national and international meetings
5

Person Profile

Education & Qualifications

Requirement
Importance
PhD in Microbiology, Molecular Genetics, or Biochemistry
Essential

Specialist Knowledge & Skills

Requirement
Importance
Molecular microbiology
Essential
Bacterial biofilms
Desirable
Pseudomonas aeruginosa
Desirable
Host-bacteria interactions
Desirable
Basic bioinformatic skills
Desirable
Statistics
Desirable
Advanced optical microscopy techniques such as deconvolution, confocal, IFM, FISH, live-cell, super-resolution
Desirable
Good publication record in peer reviewed scientific journals
Desirable
Record keeping and data management
Desirable

Relevant Experience

Requirement
Importance
Experience with bacterial culture
Essential
Experience with Pseudomonas aeruginosa molecular microbiology
Desirable
Proven record in scientific writing
Desirable
Demonstrated ability to perform research and develop novel ideas
Desirable
Preparing data / information for grant proposals
Desirable
Experience of supervising, training and mentoring visitors and students
Desirable
Experience with bacterial biofilm models
Desirable
Experience with TraDIS or RNAseq analyses
Desirable
Experience with adopting and developing techniques to address research questions
Desirable

Interpersonal & Communication Skills

Requirement
Importance
Excellent communication skills, both written and oral, including the ability to present complex information with clarity
Essential
Ability to collaborate with internal and external stakeholders
Essential
Ability to follow instructions/Standard Operating Procedures
Essential
Promotes and strives for continuous improvement
Essential
Good interpersonal skills, with the ability to work as part of a team
Essential
Demonstrated ability to work independently, using initiative and applying problem solving skills
Essential
Excellent time management and organisational skills
Essential
Ability to work under pressure and meet deadlines
Essential

Additional Requirements

Requirement
Importance
Attention to detail
Essential
Promotes equality and values diversity
Essential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to work
Essential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the Institute
Essential
Ability to maintain confidentiality and security of information where appropriate
Essential
Willingness to work outside standard working hours when required
Essential
Ability to undertake occasional travel (national and international) related to collaborations and/or seminars
Essential
Highly committed and motivated to succeed
Essential

Who We Are

Quadram Institute Bioscience

The Quadram Institute is at the forefront of a new interface between food science, gut biology and health, developing solutions to worldwide challenges in food-related disease and human health.

We are engaged in fundamental and translational food and health research, alongside clinical studies, endoscopy and industry, working together to become a leading international hub for food and health research, combining scientific excellence and clinical expertise, delivering impacts on patient care and accelerating innovation.

The Quadram Institute is a diverse and multicultural scientific community. We thrive on our international and European links, appointing staff from across the world. Any candidate who would like further information on current or anticipated immigration requirements can contact the HR Team on +44 (0)1603 450888 or nbi.recruitment@nbi.ac.uk.

For more information about working at Quadram Institute Bioscience, please click here.

Department

Microbes in the Food Chain

Group Details

The Whitchurch group is interested in understanding alternate bacterial lifestyles. In particular how bacterial communities build biofilms and produce shared resources such as extracellular DNA, moonlighting proteins and membrane vesicles. We are also interested in understanding how bacteria transition into and out of a cell wall deficient lifestyle in response to antibiotics. These lifestyle transitions confer to the bacteria the ability to withstand antibiotics, biocides and the host immune system. This project will explore the contribution of alternate bacterial lifestyles to bacterial survival, human health, infection and antimicrobial resistance.

We have expertise in a range of techniques that we use to achieve our research aims, including molecular biology, transposon mutant library screens, RNAseq, infection models, biofilms, conventional and super-resolution microscopy, live-cell imaging, and in situ hybridization.

Living in Norfolk

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Research Scientist (Bacterial Lifestyles)

Applications are invited for a Research Scientist to join the Whitchurch group at Quadram Institute Bioscience on the Norwich Research Park in the UK, to contribute to fundamental research into bacterial lifestyles.

The role:

This project will use various microscopy and molecular microbiology techniques to investigate alternate bacterial lifestyles (e.g. biofilms, cell wall deficiency) to understand their roles in the food chain, human health, and antimicrobial resistance.

The position will involve working with limited supervision to carry out individual and collaborative research projects relevant to the overall needs of the research programme. The work will also involve supervision of staff and students and general group management.

The project will exploit state of the art facilities for microscopy and genomics. QIB and the Whitchurch group will provide you with a stimulating, multidisciplinary training environment that will assist you in your successful scientific development.

The ideal candidate:

Candidates are expected to have a PhD in a relevant subject area (e.g. Microbiology, Molecular Genetics, or Biochemistry). They will have knowledge of and hands on experience with molecular microbiology.  Knowledge and skills with biofilm models, RNAseq, TRaDIS, bioinformatics, optical microscopy and quantitative image analysis are also desirable.

Additional information:

Salary on appointment will be within the range £32,578 to £39,938 per annum depending on qualifications and experience. This is a full-time post for a contract of 41 months.

Interviews will be held on 29th November 2021, with an anticipated start date in January 2022.

We are committed to equal opportunities and welcome applications from all sectors of society.  The Institute supports equality of opportunity within the workplace and expects all employees to share and display these values.  To support our commitment, we have a range of family, faith and diversity friendly working arrangements to help all staff achieve excellence in their area of work.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

About the Quadram Institute:

The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food. A partnership between Quadram Institute Bioscience, the University of East Anglia, the Norfolk and Norwich University Hospital and BBSRC, it brings together scientists and clinicians in a state-of-the-art building on the Norwich Research Park. This is one of Europe’s largest centres of life sciences and home of the John Innes Centre and The Earlham Institute. (https://quadram.ac.uk/).

The closing date for applications will be 9th November 2021.

The Quadram Institute Bioscience is a registered charity (No. 1058499) and is an Equal Opportunities Employer.